React Native promises cross-platform development and faster delivery, but enterprises face unique challenges when using it for large-scale applications. Performance limitations, restricted access to native APIs, and security concerns can impact mission-critical enterprise apps. Maintaining consistent performance, ensuring robust security, and meeting custom UI UX requirements often favor native development. Additionally, finding skilled React Native developers for enterprise-level projects can be difficult. While React Native accelerates development, enterprises must carefully weigh its benefits against these limitations. Explore alternatives like Flutter or native iOS development to achieve high performance, security, and customization in 2025.